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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ketanserin
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Serotonin mobilized intracellular Ca++ in a dose-dependent fashion … for 5-HT of 0.2 microM. Ketanserin, … Ca++ increase in a dose-dependent manner with an IC50 value of 2 nM. An initial treatment …, suggesting that 5-HT evoked an acute desensitization of 5-HT2 receptors in human platelets.”
Serotonin-induced acute desensitization of serotonin2 receptors in human platelets via a mechanism involving protein kinase C.“Sumatriptan, ketanserin , and granisetron treatment attenuated calcium accumulation and 5HT enhancement of capsaicin‐evoked CGRP release.”
Serotonin increases the functional activity of capsaicin-sensitive rat trigeminal nociceptors via peripheral serotonin receptors
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