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Last Updated: 3 years ago

Possible Interaction: Ketamine and Tubocurarine

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drug:

Ketamine

supplement:

Tubocurarine

Research Papers that Mention the Interaction

“ Tubocurarine potentiates the arterial hypotensive effect of thiopentone and reverses the hypertensive action of ketamine.”

Cardiovascular effects of tubocurarine in man

Anaesthesia • 1978 | View Paper

“This finding may help to explain clinical reports that ketamine can potentiate neuromuscular block produced by vecuronium or d-tubocurarine.”

Ketamine Decreases the Open Time of Single‐channel Currents Activated by Acetylcholine

Anesthesiology • 1988 | View Paper

“ Ketamine in 4 to 8 μg/ml Concentrations significantly (p <0.05 to 0.001) increased the neuromuscular effects of d-tubocurarine (d-Tc).”

Ketamine Interaction with Neuromuscular Blocking Agents n the Phrenic Nerve‐Hemidiaphragm Preparation of the Rat

Anesthesia and analgesia • 1978 | View Paper

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