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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ketamine
supplement:
Methionine
Research Papers that Mention the Interaction
“ Ketamine had a moderate positive inotropic effect at 10−5 M (FoC, 104% ± 5% of baseline value; P = 0.03) and 10−4 M (FoC, 107% ± 11% of baseline value; P = 0.09).”
The Inotropic and Lusitropic Effects of Ketamine in Isolated Human Atrial Myocardium: The Effect of Adrenoceptor Blockade“Preexposure of the patches to Ket revealed an additional block with a KD of approximately 2 times 10-6 M , which is below clinical concentrations.”
Ketamine Blocks Currents Through Mammalian Nicotinic Acetylcholine Receptor Channels by Interaction with Both the Open and the Closed State“ Ketamine , in concentrations of 10 −5 M –10 −3 M , reversibly blocked orthodromically induced action potentials.”
“Higher concentrations of 5 × 10 −4 M ketamine initially led to a shortening of the action potential duration, then failure of the original spontaneous activity.”
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