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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Kanamycin and Resveratrol

supplement:

Resveratrol

Research Papers that Mention the Interaction

Co-administration … concentrations of resveratrol increased the activity … aminoglycosides, including gentamicin, kanamycin , neomycin, streptomycin and tobramycin, up to 32-fold against S. aureus, while the effect was lower (2-4-fold … in minimum inhibitory concentration) for other Gram-positive pathogens (i.e. Staphylococcus epidermidis, Enterococcus faecium and Enterococcus faecalis).
International journal of antimicrobial agents  •  2018  |  View Paper
Additionally, curcumin and resveratrol increased the sensitivity of the tested bacteria to kanamycin.
Frontiers in Microbiology  •  2021  |  View Paper
However, pretreatment with resveratrol (40 and 100 μg ml-1) and quercetin (40 μg ml-1) reduced the bacteriostatic effect of kanamycin , streptomycin, cefotaxime and partially of ciprofloxacin.
World journal of microbiology & biotechnology  •  2020  |  View Paper
Resveratrol , at concentrations likely to be present during human consumption, caused a 2- to 3-fold reduction in killing during a 2-hr treatment with moxifloxacin or kanamycin.
Surprisingly, subinhibitory concentrations of resveratrol promoted (2- to 6-fold) the recovery of rifampicin-resistant mutants arising from the action of ciprofloxacin, kanamycin , or daptomycin.
PloS one  •  2016  |  View Paper