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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Kaempferol
drug:
Ritonavir
Research Papers that Mention the Interaction
“In vitro studies from our laboratory suggest that short-term exposure with pure herbal agents such as hypericin, kaempferol and quercetin or extract of SJW resulted in higher uptake or influx of ritonavir and erythromycin.”
MDR- and CYP3A4-mediated drug-herbal interactions.“Quercetin, hypericin, and kaempferol exhibited a remarkable inhibition of P-gp–mediated efflux of ritonavir by increasing its cellular uptake in these models.”
“There was a significant decrease in the Apical to Basal/Basal to Apical (AP-BL/BL-AP) transport ratio of ritonavir in presence of hypericin, kaempferol , and quercetin.”
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