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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Kaempferol
drug:
Palmitate
Research Papers that Mention the Interaction
“ Kaempferol treatment promoted viability, inhibited apoptosis and reduced caspase-3 activity in INS-1E cells and human islets chronically exposed to palmitate.”
Small molecule kaempferol modulates PDX-1 protein expression and subsequently promotes pancreatic β-cell survival and function via CREB.“In addition, luteolin significantly decreased ROS production and ameliorated lipid accumulation in HepG2 cells caused by palmitate.”
“Consistent with a role for FASN, loss of c-Met in cells treated with C75 or luteolin was prevented by exogenous addition of palmitate.”
“Again, pretreatment of luteolin could effectively reverse the effects of PA.”
“Palmitate (PA) stimulation markedly reduced insulin-mediated endothelium-dependent relaxation in rat aorta, while luteolin pretreatment effectively reversed the effects of palmitate in a concentration-dependent manner.”
Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium.
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