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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Kaempferol
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“ Kaempferol from seed coats exhibited high bioaccessibility (45.4-62.1%) and a potent inhibitor effect on Fe uptake at concentrations ranging from 0.37 to 1.30 microM. Caco-2 cell ferritin formation was used to evaluate Fe uptake.”
Bioaccessibility of phenols in common beans ( Phaseolus vulgaris L.) and iron (Fe) availability to Caco-2 cells.“A number of flavonoids, e.g., quercetin, luteolin , chrysin, and 3,6-dihydroxyflavone, have been demonstrated to chelate intracellular iron and suppress OH(•) radical production in Madin Darby canine kidney cells.”
Quercetin-iron chelates are transported via glucose transporters.“Our findings support that luteolin and iron may target the same cellular process, possibly the synthesis of sphingolipids.”
Flavonoids as Potential Drugs for VPS13-Dependent Rare Neurodegenerative Diseases“Compared with the un-fermented GLT, fermentation and complex enzymatic processing FE ) significantly increased the total phenolics, total flavonoids, quercetin and kaempferol contents by 2.1, 2.0, 13.0 and 6.8 times, respectively.”
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