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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Kaempferol
drug:
Colforsin
Research Papers that Mention the Interaction
“ Luteolin dose-dependently inhibited cAMP levels in B16 melanoma cells stimulated by 1 μM α-MSH and 1 μM forskolin , which suggest that luteolin directly inhibits adenyl cyclase in B16 melanoma cells.”
Whitening activity of luteolin related to the inhibition of cAMP pathway in α-MSH-stimulated B16 melanoma cells“Stimulation of monolayers with forskolin significantly increased their sensitivity to flavonoids: kaempferol (2.5 +/- 0.7 microM) </= apigenin (3.4 +/- 0.9 microM) </= quercetin (4.1 +/- 0.7 microM) </= genistein (6.9 +/- 2.2 microM).”
“However, luteolin (10-20 microM) produced parallel and leftward shifts of the concentration-response curve of forskolin or nitroprusside.”
Mechanisms of relaxant action of luteolin in isolated guinea pig trachea.“Stimulation of monolayers with forskolin significantly increased their sensitivity to flavonoids: kaempferol (2.5 ± 0.7 μM) ≤ apigenin (3.4 ± 0.9 μM) ≤ quercetin (4.1 ± 0.7 μM) ≤ genistein (6.9 ± 2.2 μM).”
Flavonoids stimulate Cl conductance of human airway epithelium in vitro and in vivo.
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