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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Kaempferol
drug:
Aldesleukin
Research Papers that Mention the Interaction
“The inhibitory effect of kaempferol was also observed in IL-2 but not IL-3-mediated responses and correlated with the inhibition of MLC proliferation.”
Kaempferol Inhibits IL-4-Induced STAT6 Activation by Specifically Targeting JAK31“Furthermore, catechin, epigallocatechin gallate (EGCG), epicatechin (EC), luteolin , chrysin, quercetin, and galangin increased IL-2 secretion while EGC, apigenin, and fisetin inhibited the secretion.”
“ Kaempferol suppressed IFN-gamma and IL-2 production but not that of IL-4 by T cells and shifted the Th1/Th2 balance into the Th2 phenotype.”
The flavonoid Kaempferol suppresses the graft-versus-host reaction by inhibiting type 1 cytokine production and CD8+ T cell engraftment.“ LUT also reduced the levels of glutathione and the inflammatory cytokines interleukin-2 and interferon-γ in the plasma or liver tissue.”
Modulatory effect of luteolin on redox homeostasis and inflammatory cytokines in a mouse model of liver cancer.
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