“At 10 ng/ml and 100 ng/ml, however, itraconazole induced an explosive and sustained calcium increase in both spores and hyphae.”
“These findings suggest that signal transduction via calcium might be involved in some biological effects of itraconazole on T. rubrum, and that bifonazole and ketoconazole could differently affect [Ca2+]i in T. rubrum from itraconazole.”