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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Isradipine
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Unkelback et …-term calcium entry … isradipine for 6 weeks (60 mg/kg per day) in 6to 8-week old Wistar rats reduced aortic media thickness and increased media … that the reduced media thickness is caused by cellular smooth muscle hypotrophy (thus mainly by a decrease in mean cellular volume).”
Impaired Mechanisms of Leukocyte Adhesion In Vitro by the Calcium Channel Antagonist Mibefradil“Results In thrombin- and thapsigargin-stimulated SMCs, amlodipine and not isradipine dose-dependently reduced Ca2+ mobilization (i.e. Ca2+ release from internal stores); these dihydropyridines did not affect either Ca2+ influx or ERK 1/2 activation.”
“Both phenytoin and isradipine have been shown to bind to calcium channels and to inhibit calcium entry into the cells.”
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