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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Isotretinoin and Retinyl Palmitate

Research Papers that Mention the Interaction

In contrast, single … doses of RP at 10,000 IU or 30,000 IU produced dose-related and sustained increases in Cmax and AUC0-24 h values of plasma RP, RO, RS, 13-cis- and 13-cis-4-oxo-RAs, as well as a transient increase in AT-RA.
Toxicology letters  •  2006  |  View Paper
Treatment with retinyl palmitate significantly increased the serum concentration of retinyl palmitate and of 13-cisretinoic acid but not of retinol, tocopherol or all-trans-retinoic acid. •
Graefe's Archive for Clinical and Experimental Ophthalmology  •  2006  |  View Paper
Our investigation was conducted to determine whether vitamin A retinyl palmitate ) supplementation significantly increases circulating RA concentrations of all-trans-, 9-cis-, and 13-cis-RA.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology  •  2004  |  View Paper
We have demonstrated that micromolar concentrations of HPR, retinoic acid, 13-cis-retinoic acid or Acitretin significantly reduced the in vitro hydrolysis of retinyl palmitate.
Biochimica et biophysica acta  •  1996  |  View Paper