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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Isosorbide
supplement:
Silymarin
Research Papers that Mention the Interaction
“ Silymarin co-administered with 5-ISMN resulted in further improvement of the histologic picture.”
“ Silymarin in combination with 3.6 or 7.2 mg/kg 5-ISMN resulted in 37.5 and 39.2% reductions in ALP when compared with CCl4 control group.”
“The study suggests a potential therapeutic use for 5-ISMN in combination with silymarin in liver injury.”
“When silymarin was added to 5-ISMN (1.8, 3.6 or 7.2 mg/kg), ALT decreased by 32.8, 59.6, 70.2% and AST by 28.7, 50.3, 60%, when compared with CCl4 control group levels.”
Hepatoprotective effects of the nitric oxide donor isosorbide-5-mononitrate alone and in combination with the natural hepatoprotectant, silymarin, on carbon tetrachloride-induced hepatic injury in rats
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