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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Isoproterenol
supplement:
Tryptophan
Research Papers that Mention the Interaction
“ Isoprenaline has previously been shown to cause a decrease in at least some of those plasma amino acids which compete with l-dopa and tryptophan for carrier-mediated transport into the brain.”
“The effect of isoprenaline on the concentrations of dopa and tryptophan in the brain is suggested to be at least partly caused by a change in the relationship between endogeneous and administered amino acids.”
Isoprenaline increases brain concentrations of administered l-dopa and l-tryptophan in the rat“ Isoproterenol (10 mumol/kg) caused significant increases in aromatic amino acid (tyrosine, phenylalanine and tryptophan ) levels in cerebral cortex and decreases in almost all amino acid concentrations in plasma.”
“ Isoprenaline given to rats in doses between 0.08 and 10 mg/kg intraperitoneally caused a significant decrease in plasma concentrations of tyrosine and tryptophan.”
“Abstract Intravenous infusion of anaesthetized rats with the β-adreno-receptor agonist isoprenaline decreased plasma total tryptophan concentration and increased both plasma free and brain tryptophan concentrations.”
“ Isoprenaline infusion considerably increased egress of 14 C-tryptophan from plasma and moderately increased egress of 14 C-isoleucine, but did not alter egress of 14 C-tyrosine.”
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