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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Isoproterenol
supplement:
Ribose
Research Papers that Mention the Interaction
“infusion of ribose (200 mg/kg/h) in isoproterenol-treated rats prevented the decrease of the cardiac ATP concentration induced by isoproterenol.”
Significance of the hexose monophosphate shunt in experimentally induced cardiac hypertrophy“The myocardial cell damage induced by isoproterenol was prevented by ribose.”
“The stimulatory effect of isoproterenol on myocardial adenine nucleotide biosynthesis could be further potentiated by ribose and xylitol, but not by glucose.”
“ Isoproterenol and GTP increased [3H]cyclic ADP‐ribose formation in crude membrane‐associated cyclase activity.”
“Continuous iv infusion of ribose for 5 h in unanesthetized and unrestrained rats treated with isoproterenol (25 mg/kg sc) further enhanced the available pool of 5-phosphoribosyl-1-pyrophosphate and the biosynthesis of adenine nucleotides in the myocardium.”
“Continuous intravenous infusion of ribose (200 milligrams per kilogram per hour) for 24 hours induced a marked stimulation of cardiac adenine nucleotide biosynthesis in unanesthetized and unrestrained rats that had been treated with isoproterenol subcutaneously (25 milligrams per kilogram).”
“The diminution of adenine nucleotides characteristic for the action of high doses of isoproterenol was entirely prevented, and the incidence of the isoproterenol-induced myocardial cell damage was significantly reduced when ribose was administered.”
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