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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Isoproterenol
supplement:
Procaine
Research Papers that Mention the Interaction
“Methylene blue (10(-5) M) and procaine (10(-3) M) completely blocked the direct relaxant effects of the extract and isoprenaline on the guinea-pig taenia coli.”
The relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles.“ Procaine , at 1 mM, had no effect on action potentials but reduced the maximal force responses to isoprenaline , probably by blocking sodium channels.”
“ Procaine , at 30 microM, prolonged the action potentials and augmented the force responses to isoprenaline , presumably by blocking potassium channels.”
“ Procaine , a membrane stabilizer, depresses the maximal responses of the electrically driven rat right ventricle to isoprenaline.”
“The same doses of pyrilamine, lidocaine and procaine had significantly less effects on a comparable beta adrenergic tachycardia produced by intravenous isoproterenol infusion (0.1-0.5 micrograms/kg/min i.v.)”
“ Procaine markedly reduced the hyperpolarization induced by isoprenaline (0.1 and 1 μmol 1−1) but had little effect on isoprenaline‐induced relaxation.”
“ Procaine and quinidine inhibit Ca 2+ accumulation by fraction and suppress the relaxation of this tissue induced by papaverine, isoprenaline and phenylephrine.”
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