Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Isoproterenol and Phosphatidic Acid

Research Papers that Mention the Interaction

However, longer exposure (2 minutes or more) to isoproterenol was associated with increases in the degree of P labeling of phosphatidylinositols and phosphatidic acid.
Circulation research  •  1989  |  View Paper
Analysis of 32P incorporation into individual phospholipids and polyphosphoinositides revealed that isoprenaline stimulation of the hearts was associated with a 2-3-fold increase in the degree of phosphorylation of phosphatidylinositol monophosphate and bisphosphate as well as phosphatidic acid in both cardiac homogenates and sarcoplasmic reticulum membranes.
The Biochemical journal  •  1988  |  View Paper
Lipolytic agents such as corticotropin, dibutyryl cyclic AMP, adrenaline in the presence of phentolamine and isoproterenol decreased [(32)P]P(i) incorporation into phosphatidylinositol, phosphatidylethanolamine and phosphatidic acid.
The Biochemical journal  •  1980  |  View Paper
Isoproterenol stimulated the labelling of phosphatidic acid but had no effect on phosphatidyl-inositol metabolism in the first 60 min of the incubation.
These results indicate that the main effect of isoproterenol on phospholipid metabolism in rat heart is to increase the turnover of phosphatidic acid and to slow down the conversion of phosphatidic acid into phosphatidylinositol.
Biochemical pharmacology  •  1975  |  View Paper
Under our experimental conditions, several adrenergic drugs, including DL-propranolol, phentolamine, isoproterenol , phenylephrine, but not sotalol, increased markedly (nearly up to 5-fold) the 32Pi incorporation into PhA and PhI of the iris.
Life sciences  •  1974  |  View Paper