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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Isoniazid interferes with the absorption of niacin and individuals on Isoniazid (INH) are at risk of pellagra.”
A peculiarly characterised case of isoniazid-induced pellagra- 2 Ds and a C: a case report“ Isoniazid inhibits the conversion of tryptophan to niacin and may induce pellagra, particularly in poorly nourished patients.”
“This report shows that nicotinamide inhibits protein methylation as well as tRNA methylation and describes the action of isonicotinic acid hydrazide ( INH ) on tRNA and protein methylation by partially purified rat liver methylase (2).”
Enzymatic methylations. I. Isonicotinic acid hydrazide: an inhibitor of tRNA and protein methylation.“The observations suggest a competition between isoniazid and the pyrazinamide (or its parent nicotinamide ) for a site or entrance in or on the tubercle bacilli and for sterilization, the isoniazid apparently must reach the site first.”
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