supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“We have further demonstrated that exposure of Isoniazid , Bedaquiline, Rifampicin, and O-floxacin results in higher NADH :NAD+ ratios in the Mtb residing in macrophages.”
Imaging the NADH:NAD+ Homeostasis for Understanding the Metabolic Response of Mycobacterium to Physiologically Relevant Stresses“After a short lag period, INH reacted with NADH at alkaline pH to produce superoxide radical (O2-), as detected by superoxide dismutase-inhibitable Nitro Blue Tetrazolium reduction.”
Enzymatic and nonenzymatic superoxide-generating reactions of isoniazid“ INH also inhibited both the oxidized nicotinamide adenine dinucleotide (NAD+) and adenosine 5′-monophosphate stimulation of reduced NAD ( NADH ) oxidase activity associated with the M. phlei and M. tuberculosis H37Ra electron transport particles.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback