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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Isoniazid and Manganese

drug:

Isoniazid

supplement:

Manganese

Research Papers that Mention the Interaction

“An inhibition of DNA synthesis in human fibroblasts was observed for INH , this effect being potentiated by the addition of manganese to the test system.”
The mutagenicity of isoniazid in Salmonella and its effects on DNA repair and synthesis in human fibroblasts.
Mutation research  •  1981  |  View Paper
“ Manganese at 10(-5) and 10(-4) M strongly enhanced DNA repair induced by isoniazid , iproniazid, nialamide and hydrazine.”
Enhancement by transition metals of unscheduled DNA synthesis induced by isoniazid and related hydrazines in cultured normal and xeroderma pigmentosum human cells.
Mutation research  •  1979  |  View Paper