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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Isoleucine
supplement:
Tyrosine
Research Papers that Mention the Interaction
“Both of the tyrosines and the leucine or isoleucine residues that follow them were critical.”
Interactions of p59fyn and ZAP-70 with T-cell receptor activation motifs: defining the nature of a signalling motif.“The postprandial plasma metabolites revealed a significant diet-time interaction for isoleucine (P = 0.001) and tyrosine (P = 0.001).”
“We now find that mutating two tyrosines to an isoleucine at the carboxyl end of the cytoplasmic tail cripples the ability of EBV to cause lymphoblastoid cell outgrowth, thereby marking a second transformation effector site, TES2.”
“It appears that the van der Waals interaction between the side chain of isoleucine A2 and tyrosine A19 , present in crystalline insulin, is among the most important determinants for high biological activity in insulin.”
Interaction between the A2 and A19 amino acid residues is of critical importance for high biological activity in insulin: [19-leucine-A]insulin.“Phenylalanine and tyrosine inhibit one site; proline and the straight-chain amino acids, alanine, methionine and cysteine inhibit another; and glycine and the branched-chain valine, leucine, and isoleucine inhibit a 3rd.”
“The presence of the isoleucine side chain also restricts the rotational conformation of another conserved residue in the molecule, tyrosine at position 106.”
Uncoupled Phosphorylation and Activation in Bacterial Chemotaxis
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