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Last Updated: 2 months ago

Possible Interaction: Isoleucine and Threonine

supplement:

Isoleucine

supplement:

Threonine

Research Papers that Mention the Interaction

Within the alpha1 transmembrane region, a single amino acid was identified that when mutated from threonine to isoleucine , increased furosemide sensitivity by 20-fold.
Molecular pharmacology  •  1999  |  View Paper
During infusions of isoleucine and threonine , increases (P < .05) in isoleucine carbon uptake and threonine uptake, respectively, were observed.
Diabetes  •  1987  |  View Paper
Leu alone significantly decreased Lys, Ile and Thr serum concentrations; Ile significantly decreased Thr serum concentration; combined Leu and Ile significantly decreased Thr and significantly increased Val serum concentration.
Genetics and molecular research : GMR  •  2013  |  View Paper
Increasing doses of Thr resulted in increased (P<0·05) concentrations of histidine and lysine, and decreased concentrations of isoleucine in whole-body protein.
British Journal of Nutrition  •  2006  |  View Paper
Increasing doses of Thr resulted in increased (P < 0.05) concentrations of methionine, isoleucine , histidine and lysine in whole-body protein.
The British journal of nutrition  •  1997  |  View Paper
Threonine was most effective in increasing the degree of parasitaemia but its effect was further enhanced when it was combined with dietary excess of certain other amino acids, notably valine, isoleucine and methionine.
Transactions of the Royal Society of Tropical Medicine and Hygiene  •  1984  |  View Paper
Abstract Isoleucine was found to be limiting for the growth of rats fed corn diets supplemented with lysine, tryptophan, valine, and threonine or 24% zein diets supplemented with most of the essential amino acids.
Archives of biochemistry and biophysics  •  1955  |  View Paper
We have recently demonstrated that substitution of a specific Ile with Thr was sufficient to "short circuit" the complex cyclization reaction normally catalyzed by ent-kaurene synthases to instead produce ent-pimaradiene.
Journal of the American Chemical Society  •  2007  |  View Paper
High concentrations of … allosteric inhibitor L-isoleucine ) decrease the rates of L-threonine and L-serine dehydratation and induce the appearance (at pH 6.5) or increase (at pH 7.9 and 9.5) of homotropic cooperative interactions between the active sites in the course of L-threonine dehydratation.
The enzyme inhibition by L-isoleucine increases with a decrease of L-threonine concentrations.
Biokhimiia  •  1984  |  View Paper
Reciprocal competitive inhibitions were found between threonine , aspartic acid, and isoleucine.
Plant physiology  •  1979  |  View Paper
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