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“Beginning with the age of 3 years (1.7 g protein/kg body weight/day) the intake of the AA lysine and isoleucine was three or two times higher than recommended.”
“The antiviral effect of l-lysine is partially or completely prevented by simultaneous addition of certain amino acids (l-leucine, l-isoleucine ) to the culture medium.”
Archiv für die gesamte Virusforschung • 2005 | View Paper
“ L-lysine hydrochloride supplementation of diets which contained full (i.e. with solubles added) fish meals depressed N retention, as did L-isoleucine when added at a high level (0.5%).”
Journal of the science of food and agriculture • 1975 | View Paper
“1 mM lysine inhibited the uptake of 1 mM alanine, leucine, methionine, phenylalanine, threonine and histidine but not 1 mM valine, isoleucine , tryptophan and proline by epithelial cells isolated from rat intestine.”
“ Abstract Isoleucine was found to be limiting for the growth of rats fed corn diets supplemented with lysine , tryptophan, valine, and threonine or 24% zein diets supplemented with most of the essential amino acids.”