supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Isoflurane
supplement:
Yohimbine
Research Papers that Mention the Interaction
“Smaller doses of yohimbine or atipamezole slightly increased (by 10%) the MAC of isoflurane , an increase we interpret as the result of blockade of a small amount of tonically active &agr;-adrenoreceptor activity.”
&agr;-2 Adrenoreceptors Probably Do Not Mediate the Immobility Produced by Inhaled Anesthetics“The &agr;2-adrenoceptor antagonist yohimbine inhibited isoflurane antinociception, and this effect was mediated by spinal &agr;2 adrenoceptors.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback