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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Isoflurane
supplement:
Iron, Dietary
Research Papers that Mention the Interaction
“Here, we found that ferroptosis inhibitors, ferrostatin-1 and deferoxamine mesylate (DFOM), showed great efficiency in maintaining cell viability … neuroblastoma cells exposed to a high concentration of isoflurane for 24 h. We also observed that cellular chelatable iron and lipid peroxidation were increased …-dependent manner in response to isoflurane.”
Beclin1-mediated ferroptosis activation is associated with isoflurane-induced toxicity in SH-SY5Y neuroblastoma cells.“Further, isoflurane anesthesia in chronic preparations caused an increase in the number of stalls.”
Spatio-temporal dynamics of cerebral capillary segments with stalling red blood cells“ Isoflurane (1.2 mm) reduced mean iron uptake by 46% and inhibited mitochondrial depolarization but had no effect on calcium uptake.”
“The isoflurane anesthesia increased the length of surveilling microglial processes in both acute and chronic preparations , while ketamine increased the number of microglial branches in acute preparation only.”
In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed Motility in Mouse Cortex
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