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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Isoflurane and Iron, Dietary

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

Here, we found that ferroptosis inhibitors, ferrostatin-1 and deferoxamine mesylate (DFOM), showed great efficiency in maintaining cell viability … neuroblastoma cells exposed to a high concentration of isoflurane for 24 h. We also observed that cellular chelatable iron and lipid peroxidation were increased …-dependent manner in response to isoflurane.
Acta biochimica et biophysica Sinica  •  2019  |  View Paper
Further, isoflurane anesthesia in chronic preparations caused an increase in the number of stalls.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism  •  2019  |  View Paper
Isoflurane (1.2 mm) reduced mean iron uptake by 46% and inhibited mitochondrial depolarization but had no effect on calcium uptake.
Anesthesiology  •  2001  |  View Paper
The isoflurane anesthesia increased the length of surveilling microglial processes in both acute and chronic preparations , while ketamine increased the number of microglial branches in acute preparation only.
Front. Neurosci.  •  2019  |  View Paper