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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Isoflavones and Uridine Triacetate

Research Papers that Mention the Interaction

Furthermore, the treatment of cells with isoflavones significantly reduced the microtubule-associated protein tau hyperphosphorylation by inactivating glycogen synthase kinase-3β and activating serine/threonine-protein phosphatase 2A.
Amino Acids  •  2010  |  View Paper
In conclusion, our results clearly demonstrate that isoflavones prevent ER stress-mediated neurotoxicity by inhibiting tau hyperphosphorylation in SH-SY5Y cells.
TM activated glycogen synthase kinase 3beta (GSK3beta), a kinase involved in tau phosphorylation; in contrast, isoflavones inactivated GSK3beta and decreased tau hyperphosphorylation.
Journal of medicinal food  •  2009  |  View Paper