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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Isoflavones and Steroids

supplement:

Isoflavones

Research Papers that Mention the Interaction

Furthermore, the lignan, enterolactone and the soya-derived isoflavone genistein are inhibitors of several steroid metabolising enzymes, such as aromatase, 5α-reductase and 17β-hydroxysteroid dehydrogenase.
European Urology  •  1999  |  View Paper
In addition, isoflavones interact with the metabolism of steroid hormones.
Physiological research  •  2010  |  View Paper
Altered isoflavonoid metabolism due to lack of gut bacteria may impact on steroid hormone metabolism in the body, especially estrogen metabolism.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences  •  2012  |  View Paper