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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Iron, Dietary
supplement:
Manganese Cation (2+)
Research Papers that Mention the Interaction
“As shown here, Mn(II) inhibits ferroxidase activity, suggesting that ferroxidation may be prevented in vivo as D. radiodurans accumulates a high ratio of Mn: Fe.”
Metal binding at the Deinococcus radiodurans Dps-1 N-terminal metal site controls dodecameric assembly and DNA binding.“We suggest that elevated Mn(II) displaces iron from cellular‐binding sites and the resulting rise in free iron levels leads to repression of the Fur regulon.”
“The binding of the Mn(II) Fur complex to a DNA fragment " iron box " has a slight broadening effect on the Mn(II) signal and hence it altered the symmetry of the Mn(II) environment.”
“One hundred micrograms of Mn(II) per ml and possibly 10 mug of either Co(II) or Ni(II) per ml could inhibit iron uptake in the deposition system.”
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