Possible Interaction: Iron, Dietary and Green Tea Extract

“ Green tea extract significantly reduced plasma iron vs baseline (128 to 92 μg/dL, P < .02), whereas copper, zinc, and selenium were not affected.”

“ Green tea crude extract time- and dose-dependently decreased plasma NTBI concentration and counteracted the increase of oxidative stress in both Fe 2 +-EDTA-treated human plasma and erythrocytes.”

“After treatment with GTE (0.23–2.29 &mgr;g EGCG equivalent), cellular levels of iron and ROS were dose dependently decreased.”

“ GTE from diets enriched with iron resulted to lower TAC of liver and heart than diets with GTE alone.”

“The hypothesis that iron and fat in the diet may affect green tea extract (GTE) bioactivity, in particular antioxidant capacity and gene expression, was proposed and tested in mice.”

“These results suggest that GTE may exhibit bioactivity in some organs affected by dietary fat and iron.”

“Results: Green tea decoction significantly reduced serum iron by 26% in the tea groups (p < 0.01).”

“Co-infusion of green tea extract prevented oxidative injury induced by iron.”

“Moreover, incubation with iron (1 microM) elevated lipid peroxidation of brain homogenates after 4-hour incubation at 37 degrees C. Co-incubation with green tea extract dose-dependently inhibited the iron-induced elevation in lipid peroxidation.”