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Try: Ginkgo, Methotrexate, Glucosamine

Last Updated: 3 years ago

Possible Interaction: Irinotecan and Ascorbate

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drug:

Irinotecan

supplement:

Ascorbate

Research Papers that Mention the Interaction

“The combination of pharmacological ascorbate with genotoxic agents, including oxaliplatin and irinotecan , synergistically inhibited gastric tumor growth in mouse models.”

Pharmacological Ascorbate Suppresses Growth of Gastric Cancer Cells with GLUT1 Overexpression and Enhances the Efficacy of Oxaliplatin Through Redox Modulation

Theranostics • 2018 | View Paper

“Pre-treatment of tumor cells with ascorbate leads to increased cellular sensitivity towards Docetaxel, Epirubicin, Irinotecan and 5-FU, but not towards Oxaliplatin and Vinorelbin.”

Ascorbate exerts anti-proliferative effects through cell cycle inhibition and sensitizes tumor cells towards cytostatic drugs

Cancer Chemotherapy and Pharmacology • 2010 | View Paper

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