Possible Interaction: Iopanoic Acid and Vitamin D

“When the function of D3 was inactivated by iopanoic acid (IOPA), a specific inhibitor of the enzyme, the asymmetric growth pattern in response to thyroid hormone was lost, and both dorsal and ventral CMZ grew equally.”

“Direct evidence of the importance of the intracellular conversion of T4 to T3 for TH-dependent metamorphic events was obtained in tadpoles in which endogenous TH synthesis was blocked with methimazole, and the activities of D2 and D3 were inhibited by iopanoic acid.”