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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Patients from Group A with … 131I activity of T3 and T4 showed lower specific 131I … addition of inactive iodine compared with patients from the same group with a lower initial specific 131I activity of … T4 and compared with the patient group B who was given no additional inactive iodide.”
Administration of additional inactive iodide during radioiodine therapy for Graves' disease: who might benefit?“The possible role of interference of iodine content in L-T4 is not surprising if we consider that the amount of iodine in 30 mCi is negligible (5 microg) compared with the amount of iodine content in a daily dose of T(4) ( approximately 50 microg).”
“Other factors reported by … could adversely affect levothyroxine absorption included use of prescription medications (20.6 %) and over-the-counter medications (34.3 %) used to treat comorbid …) conditions; use of dietary supplements (51.8 %, primarily calcium and iron); and intake of foods/beverages high in fiber, iodine , or ….0 %).”
“The intestinal absorption of L-T4 is prone to be impaired by a number endogenous and exogenous causes, the latter including drugs and fluids used to swallow the tablet, so that I was faced with clinical cases of L-T4 tablet malabsorption in my daily clinical practice [4-6].”
“Conclusion: In a region with a sufficient iodine supply, a 1-yr therapy with a combination of I and T4 with incomplete suppression of thyrotropin reduced thyroid nodule volume further than either component alone or placebo.”
“It is hypothesized that the maintenance of normal intrathyroidal HI is the result of the combined inhibitory effect of iodine on thyroid hormone synthesis and on the release of T4 and T3 from the thyroid.”
“The administration of iodine caused a rise in the mean serum T4, T3, and free T4 concentrations in all three siblings, but did not alter the serum Tg concentration.”
“Low levels of iodine , observed in endemic goiter areas, decrease the synthesis of T3 and T4.”
“Because excess iodine can inhibit thyroxine synthesis, an upper limit of iodine in infant formulas of 75 microg/100 kcal was proposed by the Food and Drug Administration in 1985.”
“Thallium‐201 uptake, as well as serum thyroxine and triiodothyronine, fell significantly after treatment with iodine.”
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