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“Although it is recommended to patients to avoid sea food and iodine-containing medications prior to iodine-131 (¹³¹I) scanning , the efficacy of this diet as for technetium-99m pertechnetate ((99m)Tc-P) thyroid scintigraphy is not well addressed in the literature.”
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine • 1961 | View Paper
“They reported two goitrous children, both of whom demonstrated clinical and laboratory evidence of marked hypothyroidism, and yet both accumulated more than normal amounts of iodine following tracer doses of I 131 .”
“Supplementing the control … with 4mg of iodine per day resulted in … reduction of thyroid 131 I and an increase in milk 131 I in milk, whereas 1.2g of KI per day markedly … the 131 I in milk and reduced the M/P ratio by a factor of 10.”
“Since the ratio of total iodine to I131 increases with time after processing, freshly produced I131 is necessary to make very high level labeled preparations.”