Possible Interaction: Iodine and Iodide Ion I-131

“AIM We investigated whether additional application of "cold" iodine after therapy with radioiodine could result in a prolongation of the effective half life of iodine-131 and would thus lead to an increase of the effective thyroid radiation dose.”

“Large doses of non-radioactive iodine may protect the thyroid by inhibiting radioiodine uptake into the gland (iodine blockade).”

“By administering a large dose of non-radioactive iodine the uptake of radioiodine into the gland can be inhibited ("iodine blockade").”

“I intend to show how the introduction of radioiodine contributed to stabilize the epistemic role of iodine , in both its non-radioactive and radioactive form, in thyroid gland studies and in the treatment of its disorders.”

“The therapy-induced iodine release may be one important cause for the development of hyperthyroidism in some patients during the first weeks after radioiodine therapy.”

“Since organic molecules tagged with radioiodine are often subject to dehalogenation, techniques are needed for "protecting" the iodine.”

“Freinkel and Ingbar (1955a, 1955b), Morton, Chaikoff and Rosenfeld (1944) and Fawcett and Kirkwood (1953) have established that stable iodine added to the medium interferes with accumulation of radioiodine in the thyroid slice.”

“ Radioiodine uptake into the gland can be inhibited by large doses of stable iodine or perchlorate.”

“Large doses of stable iodine affect two different steps of internalization of radioiodine (transport and organification); perchlorate affecting the transport only may be an alternative to iodine.”

“Environmental behavior of iodine is of great importance especially related to the release of radioiodine from the processing of nuclear fuel, nuclear accidents, etc.”