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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“ Iodide was found to inhibit the quinoidal chromogen formation from tyrosine and ClO2, demonstrating the preferential generation of reactive iodine in complex organic mixtures.”
Iodination of nutrients in the presence of chlorine based disinfectants used in drinking water treatment.“Abstract Thyroid peroxidase-catalyzed iodination of thyroglobulin, BSA, and tyrosine at pH 7.0 is inhibited by concentrations of iodide exceeding 1 m m .”
Thyroid peroxidase-catalyzed iodination of thyroglobulin; inhibition by excess iodide.“ I- and H2O2, in addition to their function as primary substrates …, may act as alternative 'iodine acceptors' and therefore compete with tyrosine for the active iodinating agent, irrespective of whether this compound is an enzyme-associated … (E X I delta +) or an equivalent oxidized iodine species (IOH, IC1, I2).”
“Non-enzymatic (I2-mediated) and lactoperoxidase-catalyzed iodination of tyrosine are inhibited by excess iodide ( I- ) and/or hydrogen peroxide (H2O2).”
Mechanism of enzymatic and non-enzymatic tyrosine iodination. Inhibition by excess hydrogen peroxide and/or iodide.“Excess iodide inhibits the chloroperoxidase-catalyzed iodination of tyrosine and thyroglobulin.”
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