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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Iodides and Tretinoin

supplement:

Iodides

supplement:

Tretinoin

Research Papers that Mention the Interaction

It has been suggested that retinoids have beneficial effects on iodide uptake in vitro and in humans.
European journal of endocrinology  •  2006  |  View Paper
However, when iodide uptake was stimulated by atRA , cotreatment with E(2), TOT or RAL decreased (125)I uptake in a concentration-dependent manner.
Nuclear medicine and biology  •  2011  |  View Paper
ConclusionTreatment with Dex … the presence of atRA is able to induce significant amounts of iodide accumulation in breast cancer xenotransplants in vivo due to stimulation of functional NIS protein expression, which opens exciting perspectives for a possible diagnostic and therapeutic role of radioiodine in the treatment of breast cancer.
Breast Cancer Research and Treatment  •  2007  |  View Paper
RA downregulated NIS mRNA levels, inhibited … TSH-depletion, and reduced iodide uptake to 38% after 5 d. This divergent RA-responsivity of NIS may provide the means to target radioiodide … tissue while simultaneously inhibiting iodide accumulation in normal thyrocytes and may thus re-establish the potential for radioiodide therapy.
Biochemical and biophysical research communications  •  1997  |  View Paper
It has been shown that retinoic acid RA ) alters NIS gene expression in thyroid carcinoma lines and stimulates their iodide uptake.
Nuclear medicine and biology  •  2006  |  View Paper