supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Iodides
drug:
Norepinephrine
Research Papers that Mention the Interaction
“Substitution of Cl- with I- or Br- suppressed responses to NE.”
Chloride ion currents contribute functionally to norepinephrine-induced vascular contraction.“In FRTL-5 rat thyroid cells, norepinephrine (NE) acutely depresses intracellular I- by increasing I- efflux.”
“ Norepinephrine and phenylephrine, alpha 1-agonists, increased the iodide organification in mouse thyroid lobes; however, clonidine, and alpha 2-agonist, showed a marginal effect.”
“The concentration of NE (6 X 10(-7) M) necessary to stimulate organification of iodide was 10 times less than the concentration (6 X 10(-6) M) required for inhibition of TSH-induced T4 release.”
“Substitution of Cl- with I- or Br- suppressed responses to NE.”
Chloride ion currents contribute functionally to norepinephrine-induced vascular contraction.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback