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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Iodides
drug:
Iodide Ion I-131
Research Papers that Mention the Interaction
“Uptake of iodide is a prerequisite for radioiodine therapy in thyroid cancer.”
Reestablishment of in vitro and in vivo iodide uptake by transfection of the human sodium iodide symporter (hNIS) in a hNIS defective human thyroid carcinoma cell line.“5 out of 6 patients showed a greater-than-normal suppression of radioiodine uptake by iodides.”
“However, excess iodide (50 or 200 μg KI) did suppress significantly the release of thyroidal radioiodine in all animals receiving small doses (0.1–5 mg) of PTU.”
“The inhibitory effect of excess iodide on thyroidal radioiodine release was studied in more than 300 rats.”
Inhibitory effect of excess iodide on thyroidal radioiodine release in the rat.“It is suggested that excess iodide inhibits thyroidal radioiodine release when the thyroid gland is overfunctioning.”
“Sodium, potassium, rubidium, chloride, bromide, iodide ions increased the excretion of radioiodine , while lithium, calcium, ammonium, carbonate and acetate ions did not.”
“3,9 Three main types of radioiodine uptake abnormalities have been noted in patients on iodide medication.”
THYROIDAL I-131 UPTAKE PATTERNS FOLLOWING IODIDES.“Prolonged administration of exogenous iodide resulted in a gradual decrease in radioiodine accumulation.”
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