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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Iodides
drug:
Chenodeoxycholate
Research Papers that Mention the Interaction
“All five bile acids, … in serum, chenodeoxycholic acid (CDCA), cholic acid (CA), deoxycholic acid (DCA), lithocholic acid (… (UDCA) dose-dependently inhibited both basal and TSH-induced iodide uptake at concentrations of 25-250 microM. Since CDCA is one … primary endogenous bile acids, were studied mainly the effects of CDCA.”
“These results suggest that CDCA inhibits iodide uptake by decreasing cAMP production as well as post-cAMP generation.”
“… CDCA was detected after 24 h treatment of thyroid cells, and was dependent on the time of exposure up to 72 … 72 h inhibited cAMP production stimulated by 50 mU/L TSH or 0.5 mg/L forskolin and also inhibited iodide uptake induced by 0.… mg/L forskolin.”
Effects of bile acids on iodide uptake and deoxyribonucleic acid synthesis in porcine thyroid cells in primary culture.
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