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Discover Supplement-Drug Interactions
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Last Updated: 3 months ago
supplement:
Intrinsic Factor
drug:
Lansoprazole
Research Papers that Mention the Interaction
“ Intrinsic factor concentration increased in volunteers on lansoprazole with a clear dose relationship.”
Influence of lansoprazole on intragastric 24-hour pH, meal-stimulated gastric acid secretion, and concentrations of gastrointestinal hormones and enzymes in serum and gastric juice in healthy volunteers.“Strikingly, in sulfoxidation, a significantly higher intrinsic clearance (Vmax,1/Km,1) of (–)-lansoprazole (0.023±0.001 ml/min/mg) than (+)-lansoprazole (0.006±0.000 ml/min/mg) was observed.”
“The intrinsic clearances (Clint) of the formation of both hydroxy and sulfone metabolites from S-lansoprazole were 4.9- and 2.4-fold higher than those from the R-form, respectively.”
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