Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
“Strikingly, in sulfoxidation, a significantly higher intrinsic clearance (Vmax,1/Km,1) of (–)-lansoprazole (0.023±0.001 ml/min/mg) than (+)-lansoprazole (0.006±0.000 ml/min/mg) was observed.”
European Journal of Clinical Pharmacology • 2014 | View Paper
“The intrinsic clearances (Clint) of the formation of both hydroxy and sulfone metabolites from S-lansoprazole were 4.9- and 2.4-fold higher than those from the R-form, respectively.”