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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Intralipid
drug:
Ghrelin
Research Papers that Mention the Interaction
“Whereas, somatostatin infusion alone reduced ghrelin concentration … 67%, concomitant administration of increasing amounts of intralipid … ghrelin by a further 14, 19 and 19% respectively (change in ghrelin: 0.52 +/- 0.05 vs: 0.….06, 0.72 +/- 0.09 and 0.71 +/- 0.05 microg/l; ANOVA P = 0.04).”
Free fatty acids decrease circulating ghrelin concentrations in humans.“In study 3, we reconfirmed that the low-osmolar lipid emulsion Intralipid suppresses ghrelin more weakly than isocaloric (but hypertonic) glucose.”
Hyperosmolarity in the small intestine contributes to postprandial ghrelin suppression.
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