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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interleukin-7 and Epigallocatechin Gallate

Research Papers that Mention the Interaction

Because IL-2R subunits IL-2/IL-15Rβ- and γc are shared with IL-15R and γc is shared with IL-7R, we suspected that EGCG might also influence the signaling of IL-15 and IL-7 , the two key regulators in maintaining T cell homeostasis.
Results showed that EGCG suppressed IL-15 and IL-7 signaling ; further, EGCG not only inhibited the subunits in IL-15R and IL-7R shared with IL-2R, but also affected their proprietary α chains in a manner that aligns with an impaired signaling.
The Journal of nutrition  •  2012  |  View Paper