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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Interleukin-10 and Sulforaphane

Research Papers that Mention the Interaction

SFN inhibited IL-1β and IL-10 , but tended to promote, TNF-α production by bacteria-stimulated cultures.
These results suggest that SFN has mixed effects on the placenta inhibiting both pro-inflammatory (IL-1β) and anti-inflammatory factors ( IL-10 ) but promoting regulators of oxidative stress and inflammation (HO-1 and sgp130) in an infection-dependent manner.
Journal of reproductive immunology  •  2019  |  View Paper
At the same time, SFN increased the expression of Nrf2 and heme oxygenase-1 (HO-1) as well as the production of the anti-inflammatory cytokines IL-10 and IL-4.
Cells  •  2019  |  View Paper
Furthermore, SFN significantly potentiated increased serum levels of IL-10 after LPS administration.
The Journal of nutritional biochemistry  •  2017  |  View Paper
Increases in serum tumor necrosis factor α, interleukin-6, and interleukin-10 , which were observed in GalN/LPS-treated rats, were significantly reduced after using SFN.
Nutrition research  •  2014  |  View Paper
In addition, treatment with SFN inhibited antigen-specific Th17 responses and enhanced IL-10 responses.
Experimental Neurology  •  2013  |  View Paper
Additionally, posttreatment of sulforaphane inhibited levels of IL-6, IL-10 , TNF-α, IFN-γ, and VEGF in peritoneal fluid and plasma.
Dose-response : a publication of International Hormesis Society  •  2019  |  View Paper