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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interleukin-10
supplement:
Sulforaphane
Research Papers that Mention the Interaction
“ SFN inhibited IL-1β and IL-10 , but tended to promote, TNF-α production by bacteria-stimulated cultures.”
“These results suggest that SFN has mixed effects on the placenta inhibiting both pro-inflammatory (IL-1β) and anti-inflammatory factors ( IL-10 ) but promoting regulators of oxidative stress and inflammation (HO-1 and sgp130) in an infection-dependent manner.”
Pro- and anti-inflammatory effects of sulforaphane on placental cytokine production.“At the same time, SFN increased the expression of Nrf2 and heme oxygenase-1 (HO-1) as well as the production of the anti-inflammatory cytokines IL-10 and IL-4.”
Anti-Inflammatory Effect of Sulforaphane on LPS-Activated Microglia Potentially through JNK/AP-1/NF-κB Inhibition and Nrf2/HO-1 Activation“Furthermore, SFN significantly potentiated increased serum levels of IL-10 after LPS administration.”
“Increases in serum tumor necrosis factor α, interleukin-6, and interleukin-10 , which were observed in GalN/LPS-treated rats, were significantly reduced after using SFN.”
“In addition, treatment with SFN inhibited antigen-specific Th17 responses and enhanced IL-10 responses.”
“Additionally, posttreatment of sulforaphane inhibited levels of IL-6, IL-10 , TNF-α, IFN-γ, and VEGF in peritoneal fluid and plasma.”
Sulforaphane Attenuates Endometriosis in Rat Models Through Inhibiting PI3K/Akt Signaling Pathway
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