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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interleukin-10
supplement:
Beta-Glucans
Research Papers that Mention the Interaction
“Zymosan enhanced dectin-1/TLR2/TLR4 expression and TNF-alpha/IL-10 production in all of three types of cell, whereas p-beta-glucan increased dectin-1/TLR4 and TNF-alpha/IL-12 production in AMs but inhibited IL-10 in mDCs.”
Immunomodulatory effects of beta-glucans on porcine alveolar macrophages and bone marrow haematopoietic cell-derived dendritic cells.“Stimulation of Dex-DC with beta-glucans induced a strong upregulation of Syk phosphorylation and increased secretion of IL-10 , while the production of IL-12, IL-23 and TNF-alpha was reduced.”
“Dietary supplementation of 100 mg/kg beta-glucan enhanced IL-10 concentration (p = .04) and gene expression of MUC1 and MUC2 (p < .05) in the jejunum.”
Beta-glucan from Agrobacterium sp. ZX09 improves growth performance and intestinal function in weaned piglets.“Supplementation with … of beta-glucans decreased the production of … TNF-α and increased IL-10 production, which is likely associated with key factors such as TLR4 and NF-κB. High-molecular-weight … to have a strong functional capacity to modulate the innate immune response through the Dectin-1 receptor.”
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