Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Interleukin-10 and Apigenin

supplement:

Apigenin

Research Papers that Mention the Interaction

Besides, apigenin modulated the tumor necrosis factor and IL‐10 release by microglia.
Phytotherapy research : PTR  •  2019  |  View Paper
Apigenin decrease the IL-10 expression and secretion.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2017  |  View Paper
However, apigenin inhibited the inflammation process, increased the IL-10 level and normalized the oxidative stress parameters.
Immunopharmacology and immunotoxicology  •  2016  |  View Paper
The immunomodulating effects of apigenin were also characterized by a change in the inflammatory profile as evidenced by a significant decrease in interleukin-10 and tumor necrosis factor production and increased nitric oxide levels.
Anti-cancer drugs  •  2016  |  View Paper
Apigenin also suppressed secretion of IL-17A and increased the anti-inflammatory cytokine IL-10.
American journal of physiology. Gastrointestinal and liver physiology  •  2015  |  View Paper
Apigenin exerts its effects possibly through shifting DC modulated T cell responses from T h 1 and T h 17 … the decrease in T-bet, IFN- γ ( T h 1) , IL-17 (T h 17) and increase in IL-10 , TGF-β and FoxP3 (T … donors and EAE mice.
Journal of Neuroimmune Pharmacology  •  2020  |  View Paper