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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interleukin-10
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“ IL-10 enhances corticotropin releasing factor (CRF) and corticotropin (ACTH) production in hypothalamic and pituitary tissues, respectively.”
IL-10 as a mediator in the HPA axis and brain“The intraperitoneal administration of ACTH decreased the IL-10 , IgE and histamine levels in the plasma and mast cell number in NALT, while increasing the IFN-γ level and suppressing the incidence of nasal rubbing.”
Role of Adrenocorticotropic Hormone in the Modulation of Pollinosis Induced by Pollen Antigens“Interestingly, all of the above-mentioned effects of IL-10 occur through its inhibition of ACTH effects, but not by IL-10 alone.”
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