supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Interferons
supplement:
Zinc Chloride
Research Papers that Mention the Interaction
“Conclusion: Zinc chloride inhibits HAV replication and has additive effects on the anti-HAV activities of interferon.”
Additive Effects of Zinc Chloride on the Suppression of Hepatitis A Virus Replication by Interferon in Human Hepatoma Huh7 Cells“Most important, the combined treatment of IFN and ZnCl2 reversed the IFN-mediated antiproliferative and antiviral activities, as determined by the kinetics of cell growth, thymidine incorporation, cloning efficiency, and infection with mengovirus.”
“The results show that in the … clone 11, the combined treatment of IFN … ZnCl2 reduced significantly the level of the IFN-induced 2-5A synthetase activity, the amount of the 40-, 43-, … 71-kDa 2-5A synthetase isoforms and the level of the 1.7-kb specific RNA transcript.”
Inhibition of 2-5A synthetase expression by antisense RNA interferes with interferon-mediated antiviral and antiproliferative effects and induces anchorage-independent cell growth.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback