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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Interferons and S-Adenosylmethionine

Research Papers that Mention the Interaction

Induction of ISGs in PBMCs was significantly greater during course B. In cultured cells, SAMe increased induction of ISGs and the antiviral effects of interferon by increasing STAT1 methylation, possibly affecting STAT1-DNA binding.
S-adenosyl methionine (SAMe) improves interferon signaling in cell culture.
Gastroenterology  •  2011  |  View Paper
SAM induced a synergic antiviral effect with standard IFN treatment but it was independent of IFN signaling.
World journal of gastroenterology  •  2016  |  View Paper
An increase in both AdoMet and AdoHcy was detected 3 to 6 h after addition of interferon.
The Journal of biological chemistry  •  1983  |  View Paper