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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferons
supplement:
Progesterone
Research Papers that Mention the Interaction
“The overall increase in progesterone concentration was 2-fold on day 10 in comparison to 15-30% on subsequent days even though IFN concentrations for stimulation were 2- and 4-fold higher.”
Demonstration of luteotrophic responses of human recombinant gamma interferon in porcine corpora lutea using an in-vivo microdialysis system“Neither IL-1 nor TNF alpha had significant effects on human chorionic gonadotrophin (HCG)-stimulated progesterone production, whereas IFN gamma (1-10 ng/ml) significantly reduced HCG-stimulated progesterone production by 26-37%.”
“Serum estradiol and progesterone concentrations were significantly decreased during the treatment cycle, suggesting that interferon interacts in vivo with the function of both FSH and LH.”
“Analysis of homogeneity of regression for response curves indicated that 5 mg of recombinant bovine interferon-tau decreased plasma progesterone concentrations.”
Effect of bovine interferon-tau on body temperature and plasma progesterone concentrations in cyclic dairy cows.“Low concentrations of brIFN (10(-15) mol/l to 10(-11) mol/l) stimulated progesterone secretion by granulosa cells by up to three fold, without significantly affecting oxytocin concentrations or culture DNA content.”
“ Progesterone secretion by luteal cells in serum-free culture was stimulated in the presence of 10(-15) mol/l brIFN , whilst high concentrations again caused inhibition.”
“Certain interferons have been found capable of suppressing estrogen and progesterone release.”
“ Progesterone increased IFN-τ expression in EECs.”
Interferon-τ increases BoLA-I for implantation during early pregnancy in dairy cows“ Progesterone increased IFN-τ expression in EECs.”
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