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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Interferons
supplement:
Masoprocol
Research Papers that Mention the Interaction
“ Nordihydroguaiaretic acid (NDGA), a lipoxygenase inhibitor, was found to suppress cytotoxicity in response to IFN γ and GM-CSF in both cancer patient monocytes and normal monocytes.”
The in vitro development of cytotoxicity in response to granulocyte/macrophage-colony-stimulating factor or interferon γ in the peripheral blood monocytes of patients with solid tumors: Modulation by arachidonic acid metabolic inhibitors“We also … that the IFN and the LTC4 production of spleen cells from BCG-immunized … mice was suppressed in the presence of caffeic acid and nordihydroguaiaretic acid , non-specific lipoxygenase inhibitors, and that LTC4 augmented the IFN production … normal B6 mouse spleen cells in the presence of 2-mercaptoethanol.”
Staphylococcal enterotoxin A induced interferon (IFN)-gamma production in spleen cells from BCG-immunized mice: the IFN production is dependent on leukotriene C4 but not dependent on interleukin 2.“The SEA-induced IFN production in the culture of the BCG-sensitized spleen cells was suppressed in the presence of lipoxygenase inhibitor, i.e., caffeic acid or nordihydroguaiaretic acid.”
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